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KMID : 0358820060330050672
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Journal of Korean Society of Plastic and Reconstructive Surgeons
2006 Volume.33 No. 5 p.672 ~ p.675
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Treatment of Aplasia Cuti Congenita Using Allogenic Dermal matrix and Cultured Epithelial Autograft : A Case Report
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Lee Jin-Hwa
Kim Yong-Kyu
Lee Sang-Jun
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Abstract
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Purpose:The purpose of this study is to document the surgical methods used in infants with aplasia cutis congenita treated with allogenic dermal matrix and cultured epithelial autografts.
Methods: The large defects in both lower legs were replaced with allogenic dermal matrix to avoid the postoperative hypertrophic scar contracture and a full- thickness skin biopsy was taken from right groin area simultaneously. We sent the specimen to a commercial laboratory for culture and obtained cultured epithelial autografts(Holoderm(R)) after 2 weeks, placed it over the allogenic dermal matrix.
Results:The skin-defected area were nearly epithelialized after 2 weeks and there were no significant problem on during 6 months follow-up.
Conclusions:The surgical method using allogenic dermal matrix and cultured epithelial autograft provided an excellent coverage of large skin defects of infant with aplasia cutis congenita.
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KEYWORD
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Aplasia cutis congenita, Cultured epithelial
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